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Cell Biology News
Fri, 28 Aug 2015 12:10:28 EDT
Fungi tweaked to boost industrial enzymes
Mutants of a common fungus produce endoxylanase enzymes twice as potent as the original strain.
Fri, 28 Aug 2015 11:27:37 EDT
DNA 'clews' used to shuttle CRISPR-Cas9 gene-editing tool into cells
Researchers have for the first time created and used a nanoscale vehicle made of DNA to deliver a CRISPR-Cas9 gene-editing tool into cells in both cell culture and an animal model.
Fri, 28 Aug 2015 10:22:54 EDT
Mathematician reveals the mechanism for sustaining biological rhythms
Scientists have predicted how biological circuits generate rhythms and control their robustness, utilizing mathematical modeling based on differential equations and stochastic parameter sampling.
Fri, 28 Aug 2015 08:14:54 EDT
A barcode for shredding junk RNA
A growing, dividing cell uses most of its energy store to make its "protein factories," the ribosomes. An important player in their "assembly" is the exosome, a molecular shredding machine that breaks down excess ribonucleic acid (RNA). Researchers have discovered how the exosome identifies its target RNA. The team identified a specific detection signal, comparable to a postal code or bar code that targets the exosome to the remote RNA.
Fri, 28 Aug 2015 08:13:14 EDT
Rules of communication in the nucleus: genes and nuclear pores need 'interpreters'
Nuclear pores in the nuclear membrane do not only control the transport of molecules into and out of the nucleus but also play an important role in gene expression. Researchers have deciphered a mechanism by which nuclear pores use "interpreters“ to directly influence gene expression.
Fri, 28 Aug 2015 08:13:12 EDT
Ant communication: Secrets of the antennae
Scientists have identified chemosensory proteins (CSPs) that play important roles in communications between worker ants. CSPs may represent a starting point for elucidation of the molecular mechanisms involved in the sophisticated system of communication that supports ants' complex societies, and the evolution of these mechanisms.
Thu, 27 Aug 2015 21:59:31 EDT
Meningitis: Research advances on 'scourge' of transplant wards
The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year. It's difficult to treat because fungi are genetically quite similar to humans, so compounds that affect fungi tend to have toxic side effects for patients. Now, researchers have identified 18 proteins that play a role in spore formation and germination. The findings raises the possibility of preventing the disease by blocking the spores' germination.
Thu, 27 Aug 2015 21:56:25 EDT
Chemists solve major piece of cellular mystery
Biochemists have solved the architecture of the nuclear pore complex's complicated inner ring, a subcomplex that is central to the cellular machine's ability to serve as a barrier and transport facilitator. In the process, they disproved many previously held ideas about how the inner ring works.
Thu, 27 Aug 2015 15:44:23 EDT
Scientists identify possible key in virus, cancer research
Scientists have uncovered a viral protein in the cell that inhibits the major DNA sensor and thus the body's response to viral infection, suggesting that this cellular pathway could be manipulated to help a person fight infection, cancer or autoimmune diseases.
Thu, 27 Aug 2015 15:42:51 EDT
Modified bacteria become a multicellular circuit
Scientists create a biological circuit by programming bacteria to alter gene expression in an entire population. They have created a biological equivalent to a computer circuit that involves multiple organisms to influence a population.
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