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Genetics News
Fri, 26 Aug 2016 14:23:15 EDT
Mechanical force triggers gene expression by stretching chromatin
How genes in our DNA are expressed into traits within a cell is a complicated mystery with many players, the main suspects being chemical. However, a new study has demonstrated that external mechanical force can directly regulate gene expression. The study also identified the pathway that conveys the force from the outside of the cell into the nucleus.
Fri, 26 Aug 2016 10:15:19 EDT
Allergy research: Response to house dust mites is age-dependent
In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling. This process cannot be influenced by standard cortisone therapy.
Fri, 26 Aug 2016 08:39:52 EDT
Researchers succeed in developing a genome editing technique that does not cleave DNA
A research team has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to address the existing issues of genome editing. It is expected that the technique will be applied to gene therapy in the future in addition to providing a powerful tool for breeding useful organisms and conducting disease and drug-discovery research.
Thu, 25 Aug 2016 17:22:54 EDT
Solving a 48 year old mystery: Scientists grow noroviruses in human intestinal cell cultures
For the first time, scientists have grown human noroviruses, the leading viral cause of acute diarrhea worldwide, in human intestinal cell cultures in the lab.
Thu, 25 Aug 2016 13:00:31 EDT
Scientists discover structural clues to calcium regulation in cells
The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU regulates calcium uptake has been unclear, but the recent structural discovery of a key MCU domain points toward the involvement of two ions -- calcium and magnesium -- opening new paths to the development of MCU-modulating agents for the treatment of diseases involving mitochondrial dysfunction.
Thu, 25 Aug 2016 11:32:28 EDT
Looking to saliva to gain insight on evolution
There's no need to reinvent the genetic wheel. That's one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution. The work shows that adaptation isn't just about creating new tools for survival -- it's also about tweaking the ones we have.
Wed, 24 Aug 2016 13:57:48 EDT
Scientists uncover the way a common cell enzyme alerts the body to invading bacteria
Biomedical investigators have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. In their study, the investigators provide clues to unraveling some of the mysteries surrounding the human immune system, which defends the body against harmful microbes such as bacteria.
Wed, 24 Aug 2016 11:09:10 EDT
Molecular signature shows plants are adapting to increasing atmospheric CO2
Plants are adapting to increasing atmospheric CO2 according to a new study.The research provides insight into the long-term impacts of rising CO2 and the implications for global food security and nature conservation.
Wed, 24 Aug 2016 11:09:01 EDT
New small molecule compounds could treat Ebola virus infection
Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells. The compounds could potentially be used to treat the disease after infection.
Wed, 24 Aug 2016 08:42:59 EDT
A new path for killing pathogenic bacteria
Bacteria that cause tuberculosis, leprosy and other diseases, survive by switching between two different types of metabolism. Scientists have now discovered that this switch is controlled by a mechanism that constantly adapts to meet the bacterium's survival needs, like a home's thermostat reacting to changes in temperature.
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