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Genetics News
Thu, 17 Apr 2014 09:08:36 EDT
Rapid, accurate mRNA detection in plant tissues
Messenger RNA (mRNA) plays an important role in gene expression, and examining the types and amounts of mRNA present in an organism allows researchers to answer key questions about gene expression and regulation. A recent study shows that RNAScope ISH (developed for studies in animal -- particularly human -- tissues) is faster and more sensitive than traditional ISH in detecting and quantifying mRNA in plants.
Thu, 17 Apr 2014 08:55:52 EDT
New MRSA superbug emerges in Brazil
A new superbug that caused a bloodstream infection in a Brazilian patient has been identified by an international research team. The new superbug is part of a class of highly-resistant bacteria known as methicillin-resistant Staphylococcus aureus or MRSA, which is a major cause of hospital and community-associated infections. The superbug has also acquired high levels of resistance to vancomycin, the most common and least expensive antibiotic used to treat severe MRSA infections worldwide.
Wed, 16 Apr 2014 16:26:36 EDT
Tracking down cause of eye mobility disorder
Imagine you cannot move your eyes up, and you cannot lift your upper eyelid. You walk through life with your head tilted upward so that your eyes look straight when they are rolled down in the eye socket. Obviously, such a condition should be corrected to allow people a normal position of their head. In order to correct this condition, one would need to understand why this happens. In a new paper, researchers describe how their studies on mutated mice mimic human mutations.
Wed, 16 Apr 2014 16:26:34 EDT
For cells, internal stress leads to unique shapes
A cell's unique shape results from an internal tug-of-war: the cell needs to maintain structural integrity while also dynamically responding to the pushes and pulls of mechanical stress, researchers have discovered. The researchers studied the supportive microtubule arrangement in the tissue of pavement cells from the first leaves -- or cotyledons -- of a young Arabidopsis thaliana plant.
Wed, 16 Apr 2014 16:25:16 EDT
Mutant protein in muscle linked to neuromuscular disorder
Spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. In a new study, a team of scientists say novel mouse studies indicate that mutant protein levels in muscle cells are fundamentally involved in SBMA, suggesting an alternative and promising new avenue of treatment.
Wed, 16 Apr 2014 13:33:38 EDT
Hide and seek: Revealing camouflaged bacteria
A protein family that plays a central role in the fight against the bacterial pathogen Salmonella within the cells has been discovered by researchers. The so called interferon-induced GTPases reveal and eliminate the bacterium's camouflage in the cell, enabling the cell to recognize the pathogen and to render it innocuous.
Wed, 16 Apr 2014 13:32:53 EDT
Sperm meets egg: Protein essential for fertilization discovered
Interacting proteins on the surface of the sperm and the egg have been discovered by researchers. These are essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.
Wed, 16 Apr 2014 11:30:00 EDT
DNA looping damage tied to HPV cancer, researcher discovers
Certain strains of human papillomavirus (HPV) are known to cause about five percent of all cancer cases, yet all the mechanisms aren't completely understood. Now, researchers have leveraged Ohio Supercomputer Center resources and whole-genome sequencing to identify a new way that HPV might spark cancer development -- by disrupting the human DNA sequence with repeating loops when HPV is inserted into host-cell DNA as it replicates.
Wed, 16 Apr 2014 11:28:10 EDT
Pressure relief valve in cellular membrane identified
Regulation of cell volume is critical for the body’s cells, for example during cellular exposure to fluids of varying salt concentrations, in cell division and cell growth, but also in diseases such as cancer, stroke and myocardial infarction. A certain chloride channel, a membrane protein that allows the passage of the chloride ion, is of crucial importance in volume regulation.
Wed, 16 Apr 2014 09:08:07 EDT
Diverse gene pool critical for tigers' survival, say experts
Increasing tigers' genetic diversity -- via interbreeding and other methods -- and not just their population numbers may be the best solution to saving this endangered species, according to research. Iconic symbols of power and beauty, wild tigers may roam only in stories someday soon. Their historical range has been reduced by more than 90 percent. But conservation plans that focus only on increasing numbers and preserving distinct subspecies ignore genetic diversity, according to the study. In fact, under that approach, the tiger could vanish entirely.
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