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Genetics News
Wed, 22 May 2019 15:31:33 EDT
Big energy savings for tiny machines
Physicists demonstrate for the first time a strategy for manipulating the trillions of tiny molecular nanomachines inside us that work to keep us alive, to maximize efficiency and conserve energy. The breakthrough could impact numerous fields, including creating more efficient computer chips and solar cells for energy generation.
Wed, 22 May 2019 12:05:11 EDT
Cell division requires a balanced level of non-coding RNA for chromosome stability
Scientists have discovered that centromeric DNA is used as a template to produce a non-protein coding, centromeric RNA (ribonucleic acid), that is essential for chromosome stability. If there is too much or too little centromeric RNA (cenRNA), the centromere will be defective and chromosomes will be lost.
Tue, 21 May 2019 16:24:37 EDT
Developing biosecurity tool to detect genetically engineered organisms in the wild
If a genetically or synthetically engineered organism gets into the environment, how will we tell it apart from the millions of naturally occurring microorganisms? Recently, the US government and research scientists have identified a need for new tools that can detect engineered organisms that have been accidentally or intentionally released beyond the lab. Chemical engineers are developing a detection tool based on DNA signatures.
Tue, 21 May 2019 12:40:29 EDT
After GWAS studies, how to narrow the search for genes?
Genome-wide association studies (GWAS) often turn up a long list of genes that MIGHT help cause the trait of interest. Many algorithms can help scientists prioritize which genes to pursue further, but which one to choose? Borrowing from machine learning, and singling out one chromosome at a time, a new tool called Benchmarker helps scientists evaluate existing algorithms to guide their search for relevant genes.
Tue, 21 May 2019 08:49:24 EDT
Scientists use molecular tethers, chemical 'light sabers' for tissue engineering
Researchers have unveiled a new strategy to keep proteins intact and functional in synthetic biomaterials for tissue engineering. Their approach modifies proteins at a specific point so that they can be chemically tethered to the scaffold using light. Since the tether can also be cut by laser light, this method can create evolving patterns of signal proteins throughout a biomaterial scaffold to grow tissues made up of different types of cells.
Tue, 21 May 2019 07:51:00 EDT
Dead cells disrupt how immune cells respond to wounds and patrol for infection
Immune cells prioritize the clearance of dead cells overriding their normal migration to sites of injury. A research paves the way for new therapies to manipulate how white blood cells get to and are kept at sites of injuries during healing.
Mon, 20 May 2019 12:57:59 EDT
Synthetic biologists hack bacterial sensors
Synthetic biologists have hacked bacterial sensing with a plug-and-play system that could be used to mix-and-match tens of thousands of sensory inputs and genetic outputs.
Mon, 20 May 2019 11:56:42 EDT
SABER tech gives DNA and RNA visualization a boost
A collaborative research team has now developed 'Signal Amplification by Exchange Reaction' (SABER), a highly programmable and practical method that significantly enhances the sensitivity as well as customization and multiplexing capabilities of FISH analysis.
Mon, 20 May 2019 09:34:46 EDT
Virulence factor of the influenza A virus mapped in real-time
Researchers have used high-speed microscopy to investigate native structure and conformational dynamics of hemagglutinin in influenza A.
Fri, 17 May 2019 14:41:09 EDT
Dangerous pathogens use this sophisticated machinery to infect hosts
A detailed new model of a bacterial secretion system provides directions for developing precisely targeted antibiotics.
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