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Genetics News
Tue, 27 Sep 2016 11:14:46 EDT
New switch decides between genome repair, death of cells
The genetic information of every cell is encoded in the sequence of the DNA double helix. Double strand breaks in the DNA, which can be induced by radiation, are a dangerous threat to the cells, and if not properly repaired can lead to cancer. Damaged cells need to decide whether the breaks can be fixed or whether they should be removed by a cellular suicide program called “apoptosis” before initiating cancer.
Mon, 26 Sep 2016 11:53:49 EDT
Yeast knockouts peel back secrets of cell protein function
To fill in the blanks on mitochondria, researchers deleted 174 genes, one by one, in yeast. They then subjected the yeast to high-intensity mass spectrometry to measure unprecedented detail on thousands of metabolic products, including proteins, intermediate chemicals called metabolites, and lipids.
Mon, 26 Sep 2016 10:58:37 EDT
How the anthrax toxin forms a deadly 'conveyer belt'
Researchers have built a three-dimensional map of the anthrax toxin that may explain how it efficiently transfers its lethal components into the cytoplasm of infected cells. The study suggests that the bacterial protein acts as a “conveyer belt” that allows toxic enzymes to continuously stream across cell membranes.
Fri, 23 Sep 2016 09:46:48 EDT
To produce biopharmaceuticals on demand, just add water
Researchers have created tiny freeze-dried pellets that include all of the molecular machinery needed to translate DNA into proteins, which could form the basis for on-demand production of drugs and vaccines.
Fri, 23 Sep 2016 09:44:45 EDT
Landmark map reveals the genetic wiring of cellular life
A new map breaks away from the old way of studying genes one at a time, showing how genes interact in groups to shed light on the genetic roots of diseases.
Fri, 23 Sep 2016 08:35:53 EDT
Lipid receptor fosters infection of the uterus in bitches
In the female dog, cells of the uterus can accumulate lipid droplets to form so-called foamy epithelial cells during late metoestrus. These cells produce a hormone that is involved in the implantation of the embryo in the uterus. A team of researchers has now shown for the first time that the factor assisting the cells in lipid accumulation also facilitates the binding of bacteria to the epithelial cells, resulting in serious infections of the uterus in female dogs.
Thu, 22 Sep 2016 12:39:55 EDT
Peeling back the layers: Scientists use new techniques to uncover hidden secrets of plant stem development
Innovative new cell imaging techniques have now been pioneered to shed light on cells hidden deep inside the meristem. This new development has made it possible to explore further below the outer surface of plants and has uncovered how a key gene controls stem growth.
Thu, 22 Sep 2016 09:58:58 EDT
New study of CRISPR-Cas9 technology shows potential to improve crop efficiency
A team's finding that CRISPR-Cas9 is a reliable method for multi-gene editing of this particular plant species has been released in a new article. The technology, a genome-editing tool called CRISPR-Cas9, revolutionized the life sciences when it appeared on the market in 2012. It is now proving useful in the plant science community as a powerful tool for the improvement of agricultural crops.
Thu, 22 Sep 2016 09:33:20 EDT
Researcher finds gene that reduces female mosquitoes
Placing a particular Y chromosome gene on the autosomes of Anopheles stephensi mosquitoes — a species responsible for transmitting malaria — killed off 100 percent of all female embryos that inherited this gene, researchers report.
Thu, 22 Sep 2016 08:57:43 EDT
Popeye was right: There’s energy in that spinach
Using a simple membrane extract from spinach leaves, researchers have developed a cell that produces electricity and hydrogen from water using sunlight. Based on photosynthesis, and technology paves the way for clean fuels from renewable sources.
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