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Molecular Biology News
Fri, 19 Dec 2014 16:06:04 EST
New technique reveals immune cell motion
Neutrophils, cells recruited by the immune system to fight infection, need to move through a great variety of tissues. New research shows how neutrophils move through confined spaces in the body. A new system can mimic tissues of different densities and stiffness, enabling improved development and testing of drugs.
Thu, 18 Dec 2014 21:01:00 EST
A clear, molecular view of how human color vision evolved
Many genetic mutations in visual pigments, spread over millions of years, were required for humans to evolve from a primitive mammal with a dim, shadowy view of the world into a greater ape able to see all the colors in a rainbow. Now, after more than two decades of painstaking research, scientists have finished a detailed and complete picture of the evolution of human color vision.
Thu, 18 Dec 2014 15:45:46 EST
Cell-associated HIV mucosal transmission: The neglected pathway
Scientists are challenging dogma about the transmission of the human immunodeficiency virus type 1 (HIV-1). Most research has focused on infection by free viral particles, while this group of researchers proposes that HIV is also transmitted by infected cells.
Thu, 18 Dec 2014 08:11:17 EST
Surprise gene finding on 'back or belly' decision in sea anemones
A gene that controls one of the earliest decisions in the life of an animal, where to place the back and the belly on the body, is identified in a sea anemone by researchers.
Thu, 18 Dec 2014 08:10:10 EST
Researchers discover protein protecting against chlorine
Chlorine is a common disinfectant that is used to kill bacteria, for example in swimming pools and drinking water supplies. Our immune system also produces chlorine, which causes proteins in bacteria to lose their natural folding. These unfolded proteins then begin to clump and lose their function. Now researchers have discovered a protein in the intestinal bacterium E. coli that protects bacteria from chlorine. In the presence of chlorine, it tightly bonds with other proteins, thus preventing them from coagulating.
Wed, 17 Dec 2014 11:36:56 EST
New class of synthetic molecules mimics antibodies
The first synthetic molecules that have both the targeting and response functions of antibodies have been crafted by scientists. The new molecules -- synthetic antibody mimics -- attach themselves simultaneously to disease cells and disease-fighting cells. The result is a highly targeted immune response, similar to the action of natural human antibodies.
Wed, 17 Dec 2014 10:13:12 EST
Hutchinson-Gilford Progeria syndrome: Substance from broccoli can moderate defects
Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists have now identified another important pathological factor: the system responsible for removing cellular debris and for breaking down defective proteins operates at lower levels in HGPS cells than in normal cells. The researchers have succeeded in reactivating protein breakdown in HGPS cells and thus reducing disease-related defects by using a substance from broccoli.
Wed, 17 Dec 2014 09:06:12 EST
Bugs life: The nerve cells that make locusts ‘gang up’
A team of biologists has identified a set of nerve cells in desert locusts that bring about 'gang-like' gregarious behavior when they are forced into a crowd. The findings demonstrate the importance of individual history for understanding how brain chemicals control behaviour, which may apply more broadly to humans also.
Tue, 16 Dec 2014 15:47:39 EST
Probing bacterial resistance to a class of natural antibiotics
Researchers explore the clever techniques used by bacteria to survive destruction from antimicrobial peptides -- potent defense factors produced by all living forms, including humans.
Tue, 16 Dec 2014 15:47:29 EST
New method identifies genome-wide off-target cleavage sites of CRISPR-Cas nucleases
Investigators have developed a method of detecting, across the entire genome of human cells, unwanted DNA breaks induced by use of the popular gene-editing tools called CRISPR-Cas RNA-guided nucleases.
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