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Molecular Biology News
Mon, 22 Aug 2016 15:59:32 EDT
Cells' steering wheel: New mechanism clarifies how cells migrate
Similarly to cars, cells need a steering mechanism that guides them towards a certain target or direction. Scientists have discovered the function of a key protein involved in cells' movement and clarified how cells migrate. These findings provide a deeper understanding of cells' movement and can benefit several biological fields, such as cancer, immunological and neurological research.
Mon, 22 Aug 2016 14:05:23 EDT
How cell nuclei squeeze into tight spaces
As cells move throughout our bodies, they often have to squeeze through tight nooks and crannies in their environment, reliably springing back to their original shape. The structures involved in this process are still a mystery, but now a research team reports one protein responsible for giving a cell's nucleus its durable, deformable nature. These results, the authors say, may explain the invasiveness of certain cancer cells.
Mon, 22 Aug 2016 12:49:42 EDT
Transcription factor Foxn1 and preserving immune function in later life
Researchers use new experimental models and analytical tools to investigate genes regulated by Foxn1, becoming the first to identify the DNA sequence bound by the transcription factor. Among the hundreds of genes whose expression is regulated by Foxn1 are genes essential to attract precursor cells in the blood to the thymus, that commit precursor cells to become T cells, and that provide the molecular machinery which allows T cell selection to best serve an individual.
Mon, 22 Aug 2016 12:49:34 EDT
Single-celled fungi multiply, alien-like, by fusing cells in host
Biologists report that microsporidia fuse the cells of their animal hosts together so they can multiply and quickly spread, alien-like, within their hosts' uninfected cells.
Fri, 19 Aug 2016 15:30:40 EDT
Proton pump found to regulate blood pH in stingrays
Researchers have discovered the same enzyme used by 'boneworms' to dissolve whale carcasses, and that helps promote photosynthesis in corals, also regulates blood pH in stingrays. The study could help scientists better understand the enzyme's function in human kidneys to regulate blood and urine functions.
Thu, 18 Aug 2016 16:59:48 EDT
Why Russian tuberculosis is the most infectious
Scientists conducted a large-scale analysis of the proteins and genomes of mycobacterium tuberculosis strains that are common in Russia and countries of the former Soviet Union and found features that provide a possible explanation for their epidemiological success.
Thu, 18 Aug 2016 16:59:34 EDT
In cells, some oxidants are needed
Some studies are showing that reactive oxygen species (ROS) molecules sometimes can aid in maintaining health -- findings now boosted by a surprising discovery from the researchers.
Thu, 18 Aug 2016 15:00:00 EDT
How norovirus gets inside cells: New clues
Researchers have identified the protein that norovirus uses to invade cells. Norovirus is the most common viral cause of diarrhea worldwide, but scientists still know little about how it infects people and causes disease because the virus grows poorly in the lab. The discovery, in mice, provides new ways to study a virus notoriously hard to work with and may lead to treatments or a vaccine.
Thu, 18 Aug 2016 14:59:54 EDT
Modifying a living genome with genetic equivalent of 'search and replace'
Researchers have made further progress on the path to fully rewriting the genome of living bacteria. Such a recoded organism, once available, could feature functionality not seen in nature. It could also make the bacteria cultivated in pharmaceutical and other industries immune to viruses, saving billions of dollars of losses due to viral contamination.
Thu, 18 Aug 2016 11:14:54 EDT
How cancer cells protect chromosomes from decay
Scientists have used CRISPR gene editing technology and live cell, single molecule microscopy to watch in real-time, for the first time, the essential interaction between telomerase and telomeres.
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