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Molecular Biology News
Tue, 21 Oct 2014 14:17:52 EDT
Genome editing technique advanced by researchers
Customized genome editing -- the ability to edit desired DNA sequences to add, delete, activate or suppress specific genes -- has major potential for application in medicine, biotechnology, food and agriculture. Now researchers examine six key molecular elements that help drive this genome editing system, which is known as CRISPR-Cas.
Tue, 21 Oct 2014 10:11:46 EDT
Peanut in house dust linked to peanut allergy in children with skin gene mutation
A strong link between exposure to peanut protein in household dust during infancy and the development of peanut allergy in children genetically predisposed to a skin barrier defect has been discovered by researchers.
Tue, 21 Oct 2014 10:11:38 EDT
Tarantula venom illuminates electrical activity in live cells
A cellular probe that combines a tarantula toxin with a fluorescent compound has been developed to help scientists observe electrical activity in neurons and other cells. This is the first time researchers have been able to visually observe these electrical signaling proteins turn on without genetic modification.
Mon, 20 Oct 2014 21:29:30 EDT
Plant's sunburn: How plants optimize their repair
The optimal mechanism by which plants heal the botanical equivalent of a bad sunburn has been uncovered by researchers. Their work could lead to the development of crops that can repair the sun's damage more easily, improving yields and profitability.
Mon, 20 Oct 2014 21:23:08 EDT
Scientists restore hearing in noise-deafened mice, pointing way to new therapies
Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears. By demonstrating the importance of the protein, called NT3, in maintaining communication between the ears and brain, these new findings pave the way for research in humans that could improve treatment of hearing loss caused by noise exposure and normal aging.
Mon, 20 Oct 2014 10:50:51 EDT
Protocells and information strings: Self-organizing autocatalytic network created in computer model
Protocells are the simplest, most primitive living systems, you can think of. However, creating an artificial protocell is far from simple. One of the challenges is to create the information strings that can be inherited by cell offspring, including protocells. Such information strings are like modern DNA or RNA strings, and they are needed to control cell metabolism and provide the cell with instructions about how to divide. Now using a a virtual computer experiment, researchers in Denmark have discovered information strings with peculiar properties.
Mon, 20 Oct 2014 09:01:42 EDT
Fish intake associated with boost to antidepressant response
Up to half of patients who suffer from major depression do not respond to treatment with Selective Serotonin Reuptake Inhibitors. Now a group of researchers has carried out a study that shows that increasing fatty fish intake appears to increase the response rate in patients who do not respond to antidepressants.
Mon, 20 Oct 2014 09:00:10 EDT
Structure of an iron-transport protein revealed
Iron is the most abundant trace element in humans. As a cofactor of certain proteins, it plays an essential role in oxygen transport and metabolism. Due to the major importance of iron in a wide variety of cellular processes, and the harm caused by its uncontrolled accumulation in the body, its uptake and storage is strictly regulated. In mammals, iron is imported into cells by the membrane transport protein DMT1. Mutations of DMT1, which affect its transport properties, lead to iron-related metabolic disorders such as anemia and the iron storage disease hemochromatosis.
Mon, 20 Oct 2014 09:00:08 EDT
New molecule from herb discovered, potential for drug development
A new molecule that can join together chains of amino acids -- the building blocks of protein -- has been discovered by researchers. Only three other known molecules have been discovered to be able to perform this function, which is an important process in the development of new drugs. The new molecule is able to do the same process 10,000 times faster than the other three and “cleanly” without leaving any residue behind, scientists report.
Sun, 19 Oct 2014 15:18:04 EDT
Imaging electric charge propagating along microbial nanowires
Physicists report that they've used a new imaging technique, electrostatic force microscopy, to resolve the biological debate with evidence from physics, showing that electric charges do indeed propagate along microbial nanowires just as they do in carbon nanotubes, a highly conductive human-made material.
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