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Molecular Biology News
Tue, 22 Jul 2014 14:25:17 EDT
Enhanced instrument enables high-speed chemical imaging of tissues
A research team has demonstrated a dramatically improved technique for analyzing biological cells and tissues based on characteristic molecular vibrations. The new technique is an advanced form of Raman spectroscopy that is fast and accurate enough to create high-resolution images of biological specimens, with detailed spatial information on specific biomolecules, at speeds fast enough to observe changes in living cells.
Tue, 22 Jul 2014 14:25:09 EDT
Distinctive developmental origin for a drainage tube in the eye
Scientists have conducted a comprehensive exploration of an eye structure known as Schlemm's canal: a key gatekeeper for the proper flow of eye fluid, presenting a number of insights relevant to glaucoma and other diseases.
Mon, 21 Jul 2014 15:19:20 EDT
Bioprinting methods on 2-D surfaces to link 3-D cellular structures
New research focuses on the development of a novel, matrix-free method for generating 3-D cell spheroids that are combining knowledge from bioprinting methods on 2-D surfaces to link 3-D cellular structures.
Mon, 21 Jul 2014 12:39:32 EDT
More than glitter: How gold nanoparticles easily penetrate cells, making them useful for delivering drugs
A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells. Scientists can now explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs.
Mon, 21 Jul 2014 12:38:25 EDT
Genes that contribute to radiation resistance identified
Forty-six genes in Escherichia coli have been discovered that are necessary for its survival at exceptionally high levels of radiation, researchers report in a new article. "The research has revealed new pathways of cellular self-repair, including DNA pathways that in humans that may help protect us from cancer," says a corresponding author.
Mon, 21 Jul 2014 09:59:55 EDT
When temperatures get cold, newly-discovered process helps fruit flies cope
Cold-blooded animals cannot regulate their body temperature, so their cells are stressed when facing temperature extremes. Worse still, even at slightly colder temperatures, some biological processes in the cell are slowed down more than others, which should throw the cells’ delicate chemical balance out of whack. Yet, those cells manage to keep their biological processes coordinated. Now researchers have found out how they do that.
Mon, 21 Jul 2014 09:59:51 EDT
Healing the heart with fat? 18-HEPE might help, study suggests
Too much dietary fat is bad for the heart, but the right kind of fat keeps the heart healthy, according to a new paper. Scientists in Japan have shown that mice engineered to produce their own EPA are protected against heart disease and have improved cardiac function. One particular EPA metabolite, called 18-hydroxyeicosapentaenoic acid (18-HEPE), was required for this protection.
Sun, 20 Jul 2014 20:42:19 EDT
Scientists map one of most important proteins in life -- and cancer
Scientists reveal the structure of one of the most important and complicated proteins in cell division -- a fundamental process in life and the development of cancer -- in a new research article. Images of the gigantic protein in unprecedented detail will transform scientists' understanding of exactly how cells copy their chromosomes and divide, and could reveal binding sites for future cancer drugs.
Fri, 18 Jul 2014 11:04:53 EDT
New cellular garbage control pathway with relevance for human neurodegenerative diseases
Several human neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's disease, are linked to an accumulation of abnormal and aggregated proteins in cells. Cellular 'garbage' can be removed from cells by sweeping them to a cellular recycling station known as the lysosome. Scientists have now discovered a new family of helper proteins that recognize labeled protein waste and guide them efficiently to the lysosome for destruction and recycling.
Fri, 18 Jul 2014 09:56:49 EDT
Measuring the number of protein molecules inside cells
The identification of the genes and proteins involved in a biological process, as well as the way they interact, are essential for the understanding of that process. However, often little is known about the dimensions of molecular biological structures. Knowing how many molecules make up a structure and are required for its function are essential for our understanding of biological mechanisms, yet poses a difficult challenge. Now, in a breakthrough study, researchers were able to measure the amount of protein molecules in living human cells required to form the centromere.
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