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Molecular Biology News
Thu, 26 Apr 2018 14:15:58 EDT
Who am I? How cells find their identity
A research group has investigated more closely how a single embryonic cell develops into a heart, nerve or blood cell. For the first time, the researchers have been able to reconstruct the developmental trajectories of individual embryonic cells. Their results also suggest that cells can change their path during their maturation process.
Thu, 26 Apr 2018 14:14:59 EDT
Genetic roadmap to building an entire organism from a single cell
In three landmark studies,researchers report how they have systematically profiled every cell in developing zebrafish and frog embryos to establish a roadmap revealing how one cell builds an entire organism. The findings represent a catalog of genetic 'recipes' for generating different cell types and provide an unprecedented resource for the study of developmental biology and disease.
Wed, 25 Apr 2018 13:18:41 EDT
Redefining the origin of the cellular powerhouse
Researchers proposes a new evolutionary origin for mitochondria -- also known as the 'powerhouses of the cell.' Mitochondria are energy-converting organelles that have played key roles in the emergence of complex cellular life on Earth.
Tue, 24 Apr 2018 11:29:03 EDT
A non-coding RNA lasso catches proteins in breast cancer cells
A Danish-German research team has shown that not only the where and when of long non-coding RNA expression is important for their function but also the how. The results can have a big impact on our understanding of dynamic regulation of gene expression in biological processes.
Tue, 24 Apr 2018 11:28:47 EDT
Flavins keep a handy helper in their pocket
Researchers show for the first time in detail how a flavin-containing enzyme interacts with oxygen.
Tue, 24 Apr 2018 09:37:18 EDT
New take on early evolution of photosynthesis
Scientists have begun re-thinking the evolutionary history of photochemical reaction centers (RCs). Their analysis describes a new pathway that ancient organisms may have taken to evolve the great variety of photosynthetic RCs seen today across bacteria, algae, and plants.
Mon, 23 Apr 2018 19:05:53 EDT
Wiping out the gut microbiome could help with heart failure
The bacteria that reside on and within our bodies are known to have a significant influence on our health. New research suggests wiping out the gut microbiota could improve heart functioning and potentially slow the cardiac damage that occurs with heart failure.
Mon, 23 Apr 2018 14:33:36 EDT
The role of 'extra' DNA in cancer evolution and therapy resistance
Researchers tracked genomic alterations detected in patient samples during tumor cell evolution in culture, in patient-derived xenograft (PDX) mouse models from the cultures, as well as before and after treatment in patients. The team reports that tumor progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.
Mon, 23 Apr 2018 13:50:54 EDT
Found: A new form of DNA in our cells
In a world first, researchers have identified a new DNA structure -- called the i-motif -- inside cells. A twisted 'knot' of DNA, the i-motif has never before been directly seen inside living cells.
Mon, 23 Apr 2018 11:08:07 EDT
Complete skin regeneration system of fish unraveled
Researchers have succeeded in observing the behavior of epidermal cells for the regeneration of smooth skin without remaining scar tissue using their model animal, the zebrafish.
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