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Antioxidant Action of Vitamin-C

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Description

Oxidative stress/Hypoxia is induced by a wide range of environmental factors including UV stress, pathogen invasion (hypersensitive reaction), oxygen shortage, etc. Generation of ROS (Reactive Oxygen Species) is characteristic feature of such stress conditions. Of the ROS, both Hydrogen Peroxide and Superoxide are produced in a number of cellular reactions and by various enzymes such as Lipoxygenases, Peroxidases, NADPH Oxidase, Xanthine Oxidase, etc to name a few. The main cellular components susceptible to damage by free radicals are lipids (peroxidation of unsaturated fatty acids in membranes), proteins (denaturation), carbohydrates and nucleic acids. Consequences of oxidative stress depend on tissue and/or species (i.e. their tolerance to Anoxia), on membrane properties, on endogenous antioxidant content and on the ability to induce the [...]

References:

1.The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state.
Kurutas EB.
Nutr J. 2016 Jul 25;15(1):71. doi: 10.1186/s12937-016-0186-5. Review.
2.Oxidative stress and antioxidant defense.
Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O.
World Allergy Organ J. 2012 Jan;5(1):9-19. doi: 10.1097/WOX.0b013e3182439613. Epub 2012 Jan 13.
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