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Asexual Sporulation in A. nidulans

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The signal transduction cascades regulating asexual sporulation in the Ascomycetous filamentous fungi A. nidulans (Aspergillus nidulans) can be divided into two phases: a Growth phase, in which cells become competent to respond to sporulation-inducing signals and an Asexual reproduction phase, including initiation of the Sporulation pathway and formation of spore-bearing structures. A. nidulans is homothallic (self-fertile). This fungus grows by forming an ordered network of filaments or hyphae that form a mycelium (Ref.1). The hyphae grow by apical extension and multiply by branching; giving rise to a radially symmetrical colony that expands at a constant rate. After a fixed period of time following vegetative growth, some hyphal cells within the center of the mycelium produce aerial branches that initiate asexual [...]


1.Signal transduction cascades regulating fungal development and virulence.
Lengeler KB, Davidson RC, D'souza C, Harashima T, Shen WC, Wang P, Pan X, Waugh M, Heitman J.
Microbiol. Mol. Biol. Rev. 2000 Dec;64(4):746-85.
2.The dynamic behaviour of microtubules and their contributions to hyphal tip growth in Aspergillus nidulans.
Sampson K, Heath IB.
Microbiology. 2005 May;151(Pt 5):1543-55.
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