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Biosynthesis of Steroid Hormones

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Steroid hormones are crucial substances for the proper functioning of the body. They mediate a wide variety of vital physiological functions ranging from anti-inflammatory agents to regulating events during pregnancy. Typically, endocrinologists classify steroid hormones into five major groups, based primarily on the receptor to which they bind, and the physiological outcomes: (i) Glucocorticoids (Anti-Stress Hormones), Cortisol is the major representative in most mammals; Mineralocorticoids (Ion Uptake Regulators), Aldosterone being most prominent; Androgens (Male Sex Hormones), such as Androstenedione and Testosterone; Estrogens (Female Sex Hormones), including Estrodiol and Estrone; and, Progestogens (progestational hormones), such as Progesterone. The steroid hormones are synthesized and secreted into the bloodstream by endocrine glands, such as the Adrenal Cortex and the Gonads (Ovary and Testes). [...]


1.Multiple actions of steroid hormones--a focus on rapid, nongenomic effects.
Falkenstein E, Tillmann HC, Christ M, Feuring M, Wehling M.
Pharmacol Rev. 2000 Dec;52(4):513-56.
2.Function of Cyp11a1 in animal models.
Hu MC, Hsu HJ, Guo IC, Chung BC.
Mol Cell Endocrinol. 2004 Feb 27;215(1-2):95-100.
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