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Blistering Disease

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Description

A blister (bulla) is a bubble of fluid that forms beneath a thin layer of dead skin. The fluid is a mixture of water and proteins that oozes from injured tissue. Blisters most commonly form in response to a specific injury, such as a burn or irritation, and usually involve only the topmost layers of skin. These blisters heal quickly, usually without leaving a scar. Blisters that develop as part of a systemic (bodywide) disease may start in the deeper layers of the skin and cover widespread areas. These blisters heal more slowly and may leave scars. Blistering disease is widely divided in to two catagories: Autoimmune blistering disease and inherited blistering disease. Autoimmune blistering diseases are a group of [...]

References:

1.Autoimmune blistering diseases in children.
Lara-Corrales I, Pope E.
Semin Cutan Med Surg. 2010 Jun;29(2):85-91.
2.Overview of epidermolysis bullosa.
Sawamura D, Nakano H, Matsuzaki Y.
J Dermatol. 2010 Mar;37(3):214-9.
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