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D-Alanine Metabolism in Azoarcus sp. EbN1

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Azoarcus sp. is associated with microbial degradation of aromatic and other refractory compounds, including hydrocarbons in anoxic waters and soils. Strain EbN1 is an aromatic-degrading bacteria found in freshwater and soil habitats. A unique property of strain EbN1 is its capacity to degrade toluene and ethylbenzene via two different, strictly anaerobic pathways. The absence of nitrogen fixation and specific interaction with plants separates EbN1 ecophysiologically from the closely related nitrogen-fixing plant symbionts of the Azoarcus cluster (Ref.1). A key step in peptidoglycan layer assembly and deposition in the cell wall of Azoarcus is the subsequent enzymic cross-linking of one peptidoglycan strand to an adjacent one in cell wall growth. D-Alanine is a central molecule in this peptidoglycan assembly and cross-linking. [...]


1.The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1.
Rabus R, Kube M, Heider J, Beck A, Heitmann K, Widdel F, Reinhardt R.
Arch Microbiol. 2005 Jan; 183(1):27-36. Epub 2004 Nov 13.
2.Characterization of the alanine racemases from two mycobacteria.
Strych U, Penland RL, Jimenez M, Krause KL, Benedik MJ.
FEMS Microbiol Lett. 2001 Mar 15;196(2):93-8
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