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D-Alanine Metabolism in B. anthracis A2012

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Description

Bacilli are an extremely diverse group of bacteria that include both the causative agent of anthrax (Bacillus anthracis) as well as several species that synthesize important antibiotics. Bacilli are rod-shaped, Gram-positive, sporulating, aerobes or facultative anaerobes. Bacilli exhibit an array of physiologic abilities that allow them to live in a wide range of habitats, including many extreme habitats such as desert sands, hot springs, and Arctic soils. Species in the genus Bacillus can be thermophilic, psychrophilic, acidophilic, alkaliphilic, halotolerant, or halophilic and are capable of growing at pH values, temperatures, and salt concentrations where few other organisms can survive (Ref.1, 2 & 4). Due to the metabolic diversity in the genus Bacillus, Bacilli are able to colonize a variety of [...]

References:

1.Characterization of a Bacillus anthracis isolate causing a rare case of fatal anthrax in a 2-year-old boy from Hong Kong.
Cheung DT, Kam KM, Hau KL, Au TK, Marston CK, Gee JE, Popovic T, Van Ert MN, Kenefic L, Keim P, Hoffmaster AR.
J Clin Microbiol. 2005 Apr; 43(4):1992-4.
2.The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria.
Read TD, Peterson SN, Tourasse N, Baillie LW, Paulsen IT, Nelson KE, Tettelin H, Fouts DE, Eisen JA, Gill SR, Holtzapple EK, Okstad OA, Helgason E, Rilstone J, Wu M, Kolonay JF, Beanan MJ, Dodson RJ, Brinkac LM, Gwinn M, DeBoy RT, Madpu R, Daugherty SC, Durkin AS, Haft DH, Nelson WC, Peterson JD, Pop M, Khouri HM, Radune D, Benton JL, Mahamoud Y, Jiang L, Hance IR, Weidman JF, Berry KJ, Plaut RD, Wolf AM, Watkins KL, Nierman WC, Hazen A, Cline R, Redmond C, Thwaite JE, White O, Salzberg SL, Thomason B, Friedlander AM, Koehler TM, Hanna PC, Kolsto AB, Fraser CM.
Nature. 2003 May 1; 423(6935):81-6.
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