About Us
Contact Us
Login to Protein Lounge!

Glutathione Metabolism

This image is a scaled-down version of the actual pathway image. It does not contain any links to the protein information pages.


Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. It is composed of Glutamate, Cysteine and Glycine that has numerous important functions within cells. Glutathione is homeostatically controlled, both inside the cell and outside. It often attains millimolar levels inside cells, which makes it one of the most highly concentrated intracellular antioxidants. Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as Glutathione Disulfide or GSSG. The GSSG/Gsh ratio may be a sensitive indicator of [...]


1.[Gamma Glutamyltransferase]
Yoshikawa C, Naka K, Shimojo N, Ohkawa J.
Nippon Rinsho. 1995 May; 53(5):1162-7.
Bittner S, Win T, Gupta R.
Amino Acids. 2005 Apr 21.
You can get all the details on this pathway through subscription