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Glutathione Metabolism in C. glutamicum

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Corynebacterium glutamicum is a Gram-positive, non pathogenic and fast growing soil bacterium with special biotechnological importance C. glutamicum is an amino acid producing soil bacterium. A typical feature of this organism is the formation of V-shaped structures of dividing cells, called "snapping division". C. glutamicum is used for industrial amino acid production and hence grown in bioreactors under control of the process parameters (Ref. 1).

Glutathione is a thiol compound, present in the highest concentration in all types of cells. It is composed of Glutamate, Cysteine and Glycine, and has numerous important functions within the C. glutamicum cell. Glutathione metabolism in C. glutamicum occurs within cells in two closely linked, enzymatically controlled reactions that utilize ATP and draw on nonessential amino [...]


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