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Description |
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Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor.
It is ubiquitous in animals, plants, and microorganisms, and being water soluble
is found mainly in the cell cytosol and other aqueous phases of the living
system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine
that has numerous important functions within cells. It is homeostatically
controlled, both inside the cell and outside and often attains millimolar levels
inside cells, which makes it one of the most highly concentrated intracellular
antioxidants. Glutathione exists in two forms. The antioxidant "reduced
Glutathione" tripeptide is conventionally called Glutathione and abbreviated
Gsh; the oxidized form is a sulfur-sulfur linked compound, known as Glutathione
Disulfide or GSSG. The GSSG/Gsh ratio may be a sensitive [...] |
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References:
1. Genomic diversity of enterohemorrhagic Escherichia coli O157 revealed by whole genome PCR scanning.Ohnishi M, Terajima J, Kurokawa K, Nakayama K, Murata T, Tamura K, Ogura Y, Watanabe H, Hayashi T.Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):17043-8.2. Massive outbreak of Escherichia coli O157:H7 infection in schoolchildren in Sakai City, Japan, associated with consumption of white radish sprouts.Michino H, Araki K, Minami S, Takaya S, Sakai N, Miyazaki M, Ono A, Yanagawa H.Am J Epidemiol. 1999 Oct 15; 150(8):787-96.
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