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Description |
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Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor.
It is ubiquitous in animals, plants, and microorganisms, and being water soluble
is found mainly in the cell cytosol and other aqueous phases of the living
system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine
that has numerous important functions within cells. Glutathione is
homeostatically controlled, both inside the cell and outside. It often attains
millimolar levels inside cells, which makes it one of the most highly
concentrated intracellular antioxidants. Glutathione exists in two forms. The
antioxidant "reduced Glutathione" tripeptide is conventionally called
Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked
compound, known as Glutathione Disulfide or GSSG. The GSSG/Gsh ratio may be a
sensitive [...] |
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References:
1. [Gamma Glutamyltransferase]Yoshikawa C, Naka K, Shimojo N, Ohkawa J.Nippon Rinsho. 1995 May; 53(5):1162-7.2. Is serum gamma glutamyltransferase a marker of oxidative stress?Lee DH, Blomhoff R, Jacobs DR Jr.Free Radic Res. 2004 Jun; 38(6):535-9.
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