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Description |
Methylococcus capsulatus is an obligate, Gram-negative methanotroph.
Methanotrophs are responsible for the oxidation of biologically generated
methane and therefore help reduce the amount of greenhouse gas that is released
to Earth s atmosphere. The conversion of methane to biomass by M.
capsulatus has been exploited for large-scale commercial production of
microbial proteins by fermentation. Thus, the bacterium plays major roles in
global carbon cycles, and in particular, substantially reduces emissions of
biologically generated methane to the atmosphere. M. capsulatus genome
is highly specialized for a methanotrophic lifestyle, including redundant
pathways, predicted to be involved in methanotrophy and duplicated genes for
essential enzymes such as the methane monooxygenases (Ref.1).
Glutathione
metabolism in M. capsulatus involves both the synthesis of Glutathione
and its catabolism. [...] |
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References:
1. Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath).Ward N, Larsen O, Sakwa J, Bruseth L, Khouri H, Durkin AS, Dimitrov G, Jiang L, Scanlan D, Utterback T, Feldblyum TV, Fraser CM, Lillehaug JR, Eisen JA et al.PLoS Biol. 2004 Oct; 2(10):e303.2. A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.Minami H, Suzuki H, Kumagai H.FEMS Microbiol Lett. 2003 Jul 29; 224(2):169-73
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