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Description |
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Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor.
It is ubiquitous in animals, plants, and microorganisms, and being water soluble
is found mainly in the cell cytosol and other aqueous phases of the living
system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine
and has numerous important functions within the Mycobacterium cells.
Mycobacteria are Gram-positive, non-motile, pleomorphic rods shaped bacteria
related to the Actinomyces. Most Mycobacteria are found in habitats such as
water or soil. However, a few are intracellular pathogens of animals and humans.
M. tuberculosis causes the disease known as tuberculosis. It has the
potential to manufacture all of the machinery necessary to synthesize all its
essential vitamins, amino acids, and enzyme co-factors. M. [...] |
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References:
1. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.Camus JC, Pryor MJ, Medigue C, Cole ST.Microbiology. 2002 Oct; 148(Pt 10):2967-73.2. Is serum gamma glutamyltransferase a marker of oxidative stress?Lee DH, Blomhoff R, Jacobs DR Jr.Free Radic Res. 2004 Jun; 38(6):535-9.
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