This image is a scaled-down version of the actual pathway image. It does not contain any links to the protein information pages.
|
|
Description |
Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor.
It is ubiquitous in animals, plants, and microorganisms, and being water soluble
is found mainly in the cell cytosol and other aqueous phases of the living
system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine
that has numerous important functions within cells. Glutathione is
homeostatically controlled, both inside the cell and outside. It often attains
millimolar levels inside cells, which makes it one of the most highly
concentrated intracellular antioxidants. Glutathione exists in two forms. The
antioxidant "reduced Glutathione" tripeptide is conventionally called
Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked
compound, known as Glutathione Disulfide or GSSG.
Glutathione is
synthesized from its constituent amino acids [...] |
|
|
References:
1. Is serum gamma glutamyltransferase a marker of oxidative stress?Lee DH, Blomhoff R, Jacobs DR Jr.Free Radic Res. 2004 Jun; 38(6):535-9.2. Nocardia farcinica arthritis of the knee. A case report.Audenaert E, Almafragi A, Vuylsteke M, Verdonckt C, Verdonk R.Acta Orthop Belg. 2004 Aug; 70(4):386-8.
|
|
|
|
|