Quantcast
ProteinLounge
Citations
About Us
Contact Us
Login to Protein Lounge!

Glutathione Metabolism in N. meningitides Z2491

This image is a scaled-down version of the actual pathway image. It does not contain any links to the protein information pages.
 

Description

Neisseria meningitidis is a causative agent of meningitis, and is responsible for considerable morbidity and mortality throughout the world. Most disease-causing N. meningitidis strains belong to Serogroups A, B and C. Serogroup A strains are responsible for major epidemics and pandemics of meningococcal disease, and therefore most of the morbidity and mortality associated with this disease, and Serogroup B and C strains are responsible for outbreaks of menigitis in the developed world. N. meningitidis resides in its natural habitat within the nasopharyngeal tract of humans. These meningococci are opportunistic pathogens that colonize the nasopharynges and oropharynges of asymptomatic carriers. They occasionally gain access to the blood, and subsequently to the cerebrospinal fluid, to cause septicaemia and meningitis (Ref.1).

Glutathione metabolism in [...]

References:

1.Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491.
Parkhill J, Achtman M, James KD, Bentley SD, Churcher C, Rutherford KM, Simmonds M, Skelton J, Whitehead S, Spratt BG, Barrell BG et al.
Nature 2000 Mar 30; 404(6777):502-6
2.A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity.
Minami H, Suzuki H, Kumagai H.
FEMS Microbiol Lett. 2003 Jul 29; 224(2):169-73.
You can get all the details on this pathway through subscription