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Glutathione Metabolism in X. fastidiosa Temecula-1

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Xylella fastidiosa is a Gram-negative, fastidious, xylem-limited bacterium that causes a range of economically important plant diseases. It causes citrus variegated chlorosis-a serious disease of orange trees. It is responsible for pathogenicity and virulence involving toxins, antibiotics and ion sequestration systems (Ref.1 & 2). X. fastidiosa Temecula-1 is 2.52MB. It is isolated from a naturally infected grapevine with Pierce s disease in a wine-grape-growing region of California. This disease is characterized by wilted, shriveled, raisin-like fruits and scorched leaves that detach, leaving bare petioles attached to the canes. This devastating disease is a major threat to the viability of the California wine industry (Ref.3).

Glutathione is a tripeptide present in Xylella sp., which is composed of Glutamate, Cysteine and Glycine, and has [...]


1.Stable transformation of the Xylella fastidiosa citrus variegated chlorosis strain with oriC plasmids.
Monteiro PB, Teixeira DC, Palma RR, Garnier M, Bove JM, Renaudin J.
Appl Environ Microbiol. 2001 May; 67(5):2263-9.
2.The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis.
Simpson AJ, et al.
Nature. 2000 Jul 13; 406(6792):151-7.
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