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Glycine and Serine Metabolism in M. capsulatus

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Description

Methylococcus capsulatus is an obligate, Gram-negative methanotroph. It generally use the greenhouse gas Methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular, substantially reducing emissions of biologically generated Methane to the atmosphere. Methylococcus capsulatus is the first complete genome sequence reported from an obligate methanotroph. Genome analysis suggests the ability of M. capsulatus to scavenge copper (including a previously unreported nonribosomal peptide synthetase) and to use copper in regulation of methanotrophy, but the exact regulatory mechanisms remain unclear. The existence of previously unsuspected metabolic flexibility in M. capsulatus, including an ability to grow on sugars, oxidize chemolithotrophic hydrogen and sulfur, and live under reduced oxygen tension, all of [...]

References:

1.Insights into the obligate methanotroph Methylococcus capsulatus.
Kelly DP, Anthony C, Murrell JC.
Trends Microbiol. 2005 May;13(5):195-8.
2.Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath).
Ward N, Larsen O, Sakwa J, Bruseth L, Khouri H, Durkin AS, Dimitrov G, Jiang L, Scanlan D, Kang KH, Lewis M, Nelson KE, Methe B, Wu M, Heidelberg JF, Paulsen IT, Fouts D, Ravel J, Tettelin H, Ren Q, Read T, DeBoy RT, Seshadri R, Salzberg SL, Jensen HB, Birkeland NK, Nelson WC, Dodson RJ, Grindhaug SH, Holt I, Eidhammer I, Jonasen I, Vanaken S, Utterback T, Feldblyum TV, Fraser CM, Lillehaug JR, Eisen JA.
PLoS Biol. 2004 Oct;2(10):e303. Epub 2004 Sep 21.
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