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Glycine, Serine and Threonine Metabolism in D. radiodurans

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Description

The bacterium D. radiodurans (Deinococcus radiodurans) is a Gram-positive, red-pigmented, non-motile bacterium that shows remarkable resistance to a range of damage caused by ionizing radiation, desiccation, UV radiation, oxidizing agents, and electrophilic mutagens. D. radiodurans is best known for its extreme resistance to ionizing radiation; not only can it grow continuously in the presence of chronic radiation, but also it can survive acute exposures to Gamma radiation without dying or undergoing induced mutation. The RecA (Recombinase-A) protein of D. radiodurans is essential for the extreme radiation resistance of this organism. The biochemical metabolism of Glycine, Serine and Threonine provides amino acids like Glycine, which is highly essential to maintain viability of RecA protein. In order to maintain the fidelity of protein synthesis and protein [...]

References:

1.Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance.
Omelchenko MV, Wolf YI, Gaidamakova EK, Matrosova VY, Vasilenko A, Zhai M, Daly MJ, Koonin EV, Makarova KS.
BMC. Evol. Biol. 2005 Oct 20;5:57.
2.Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics.
Makarova KS, Aravind L, Wolf YI, Tatusov RL, Minton KW, Koonin EV, Daly MJ.
Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics.
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