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Glycine, Serine and Threonine Metabolism in E. coli K-12

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The bacterium E. coli (Escherichia coli) is one of the best and most thoroughly studied free-living organisms. It is also a remarkably diverse species because some E. coli strains live as harmless commensals in animal intestines, whereas other distinct genotypes including the enteropathogenic, enterohemorrhagic, enteroinvasive, enterotoxigenic, and enteroaggregative E. coli causes significant morbidity and mortality as human intestinal pathogens (Ref.1). Extra-intestinal E. coli are another varied group of life-threatening pathogens of this manifestly versatile species. This latter group of pathogens includes distinct clonal groups responsible for neonatal meningitis/sepsis and urinary tract infections. E. coli is Gram-negative, flagellated and members of the strain E. coli K-12 are non-pathogenic. The involvement of D- and L-Amino acid metabolism like L-Serine, D-Serine, L-Threonine and [...]


1.Identification of an Escherichia coli operon required for formation of the O-antigen capsule.
Peleg A, Shifrin Y, Ilan O, Nadler-Yona C, Nov S, Koby S, Baruch K, Altuvia S, Elgrably-Weiss M, Abe CM, Knutton S, Saper MA, Rosenshine I.
J. Bacteriol. 2005 Aug;187(15):5259-66.
2.Determination of functional interactions among signalling pathways in Escherichia coli K-12.
Yang YL, Liao JC.
Metab Eng. 2005 Jul 4.
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