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Glycine, Serine and Threonine Metabolism in G. sulfurreducens

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G. sulfurreducens (Geobacter sulfurreducens), a delta-proteobacterium, is an obligately anaerobic, non-fermentative, non-motile, Gram-negative rod. Geobacter species are of interest because of their novel electron transfer capabilities, impact on the natural environment and their application to the Bioremediation of contaminated environments and harvesting electricity from waste organic matter. G. sulfurreducens breaks down heavy metals and is being used to clean up toxic metal waste sites like Uranium, etc. Central to the metabolism of G. sulfurreducens is the ability to anaerobically oxidize Acetate (an abundant electron donor and carbon source in subsurface zones) completely to CO2 (Carbondioxide) and water using a variety of electron acceptors including metal ions, elemental Sulfur, and Fumarate. The genera Geobacter and Desulfuromonas comprise dissimilative metal-reducing bacteria, which cannot reduce [...]


1.Stimulating the in situ activity of Geobacter species to remove uranium from the groundwater of a uranium-contaminated aquifer.
Anderson RT, Vrionis HA, Ortiz-Bernad I, Resch CT, Long PE, Dayvault R, Karp K, Marutzky S, Metzler DR, Peacock A, White DC, Lowe M, Lovley DR.
Appl. Environ. Microbiol. 2003 Oct;69(10):5884-91.
2.Genome of Geobacter sulfurreducens: metal reduction in subsurface environments.
Methe BA, Nelson KE, Eisen JA, Paulsen IT, Nelson W, Heidelberg JF, Wu D, Wu M, Ward N, Beanan MJ, Dodson RJ, Madupu R, Brinkac LM, Daugherty SC, DeBoy RT, Durkin AS, Gwinn M, Kolonay JF, Sullivan SA, Haft DH, Selengut J, Davidsen TM, Zafar N, White O, Tran B, Romero C, Forberger HA, Weidman J, Khouri H, Feldblyum TV, Utterback TR, Van Aken SE, Lovley DR, Fraser CM.
Science. 2003 Dec 12;302(5652):1967-9.
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