S. typhimurium (Salmonella enterica subspecies I, serovar Typhimurium), is a leading cause of human Gastroenteritis, and is used in mouse models of human Typhoid fever. The genus Salmonella comprises two species: S. enterica, which is subdivided into over 2,000 serovars, and S. bongori (Salmonella bongori). Some serovars of S. enterica, such as S. typhi, cause systemic infections and Typhoid fever, whereas others, such as S. typhimurium, cause Gastroenteritis. Some serovars, such as S. typhi, are host specialists that infect only humans, whereas others such as S. typhimurium are host generalists that occur in humans and many other mammalian species. Domestic animals act as a reservoir for the food-borne spread of host-generalist serovars, which accounts for the high incidence of non-typhoid [...]