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Glycine, Serine and Threonine Metabolism in Y. pestis Mediaevails

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Description

Y. pestis (Yersinia pestis) is rod shaped, Gram-negative, and non-motile but has two distinct flagellar gene clusters; one set is incomplete and the other produces a truncated protein, which acts as a transcriptional activator for the flagellar genes. Y. pestis, a Group-A bioterrorism agent, causes Plague, a re-emerging zoonotic disease transmitted to humans through flea bites and typically characterized by the appearance of a tender and swollen lymph node, the bubo. It is believed that Y. pestis is a clone that evolved from Y. pseudotuberculosis (Yersinia pseudotuberculosis) about 1.5 to 20 thousand years ago. Y. pestis is primarily a rodent pathogen, with humans being an accidental host when bitten by an infected rat flea (Ref.1). The rodents’ fleas, such as [...]

References:

1.Community-acquired pneumonia in the age of bio-terrorism.
Dattwyler RJ.
Allergy. Asthma. Proc. 2005 May-Jun;26(3):191-4.
2.Plague Bacteria Target Immune Cells During Infection.
Marketon MM, Depaolo RW, Debord KL, Jabri B, Schneewind O.
Science. 2005 Jul 28.
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