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Life Cycle of Plasmodium falciparum

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Description

Malaria is the world s largest parasitic disease, killing more people than any other communicable disease except Tuberculosis. Malaria is a major public health problem in more than 100 countries, inhabited by a total of some 2.4 billion people, or close to half of the world s population. Each year, 300–500 million people contract malaria and about 3 million die, most of which are children under five years old. In absolute numbers, malaria kills 3,000 children per day under the age of five. The total number of deaths readily exceeds that from AIDS. Human malaria is caused by infection with intracellular protozoan parasites of the genus Plasmodium that are transmitted by Anopheles mosquitoes. Four species of Plasmodium infect humans: P. falciparum, P. [...]

References:

1.Serial analysis of gene expression in Plasmodium falciparum reveals the global expression profile of erythrocytic stages and the presence of anti-sense transcripts in the malarial parasite.
Patankar S, Munasinghe A, Shoaibi A, Cummings LM, Wirth DF.
Mol Biol Cell. 2001 Oct;12(10):3114-25.
2.A parasite genome sheds light on an old enemy.
Cowman AF, Crabb BS.
Nat Biotechnol. 2002 Nov;20(11):1098-9.
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