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Sterol Biosynthesis in A. thaliana

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Sterols are a structurally conserved class of lipids that play multifaceted roles in Eukaryotes, serving as essential components of Cell membranes and precursors to Steroid hormones. Characterized by a –OH group on the C3 of the Steroid nucleus, Sterols represent the most abundant type of Steroids in Vertebrates as well as in Plants. In Vertebrates, Cholesterol is by far the major Sterol, whereas a mixture of various Sterols is present in higher plants. The major Sterol is typically Sitosterol, followed by Campesterol, Stigmasterol, and various minor sterols like Isofucosterol, Brassicasterol and Cholesterol. Functional roles for the Campesterol-derived BRs (Brassinosteroids) are established for integrating light signals in the regulation of postembryonic plant growth. Specific biological roles for Sitosterol and other less [...]


1.The role of sterols in plant growth and development.
Schaller H.
Prog Lipid Res. 2003 May;42(3):163-75.
2.Arabidopsis mutants reveal multiple roles for sterols in plant development.
Clouse SD.
Plant Cell. 2002 Sep;14(9):1995-2000.
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