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Description |
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Phosphoglycerides such as phosphatidylethanolamine and phosphatidylserine are
the major component of lipid bilayer membranes in which their detergent-like
properties help to provide membranes the quality of self-assembly.
Phosphatidylglycerol is a precursor in the synthesis of both cardiolipin and PI
(Phosphatidylinositol). Cardiolipin is a unique dimeric phospholipid found in
the heart and most mammalian tissues. This phospholipid is the only phospholipid
localized primarily in the mitochondrial membrane of mammalian cells. In
cardiolipin, two phosphatidylglycerol units are joined together. Phosphatidic
acid is activated to CDP-DAG (CDP-Diacylglycerol), which is the precursor to PI
and cardiolipin. PI is the precursor of PI Phosphates, which have one of more
phosphates on the inositol. Hydrolysis of various phosphorylated PI produces DAG
and phosphorylated inositides that are [...] |
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