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Transcription of rRNA

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rRNA (Ribosomal RNA) is the central component of the Ribosome, the protein manufacturing machinery of all living cells. The rRNA is synthesized in the nucleolus. These machines then self-assemble into the two complex folded structures (the large 60S and the small 40S subunits) in the presence of 70 – 80 rProteins (Ribosomal Proteins). The function of the rRNA is to provide a mechanism for decoding mRNA into amino acids (at center of small ribosomal subunit) and to interact with the tRNAs during translation by providing peptidyl transferase activity (large subunit). Accuracy of translation is provided by both subunits. In Bacteria, Archaea, Mitochondria, and Chloroplasts a small ribosomal subunit contains the 16S rRNA, where the S in 16S represents Svedberg units; [...]


1.A new paradigm for the regulation of the mammalian ribosomal RNA genes.
Moss T, Stefanovsky V, Langlois F, Gagnon-Kugler T.
Biochem Soc Trans. 2006 Dec;34(Pt 6):1079-81.
2.Factors responsible for modulation of ribosomal RNA transcription.
Wnuk M, Slota E, Kotylak Z, Bugno M.
Folia Biol (Krakow). 2006;54(1-2):1-8.
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