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Yersinia Infection

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Description

Yersinia pestis, a gram-negative bacillus, which is responsible for causing bubonic plague, is considered by the Center for Disease Control to be one of the top 5 bioterrorist agents. After infection, the pathogen invades lymphatic tissues and proliferates in the lymph nodes, and symptoms of pneumonic plague are expressed when the organism infects the lungs (Ref.1). The pneumonic plague is highly contagious, with transmission occurring between people via respiratory droplets. The mortality rate of untreated pneumonic plague is almost 100 percent. Altough pneumonic plague is contagious, advances in living conditions, along with public health advances and antibiotics, make natural epidemics of the plague improbable. However, biological terrorist outbreaks of the plague pose a serious threat. A bioterrorism attack by aerosolized [...]

References:

1.The induction of apoptosis by bacterial pathogens.
Weinrauch Y, Zychlinsky A.
Annu Rev Microbiol. 1999;53:155-87. Review.
2.[The plague, possible bioterrorist act]
Bossi P, Bricaire F.
Presse Med. 2003 May 17;32(17):804-7. Review. French.
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