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Pubmed Ahead
1: Structural and physico-chemical determinants of the interactions of macrocyclic photosensitizers with cells. Complete details PMID:17628795
Mojzisova H Bonneau S Brault D
Eur Biophys J 36 8 943-53 , 2007 Nov
New therapies have been developed using reactive oxygen species produced by light-activation of photosensitizers (PS). Since the lifetime of these species is extremely short and their diffusion in space
2: Molecular dynamics simulation approach for the prediction of transmembrane helix-helix heterodimers assembly. Complete details PMID:17646979
Samna Soumana O Garnier N Genest M
Eur Biophys J 36 8 1071-82 , 2007 Nov
Computational methods are useful to identify favorable structures of transmembrane (TM) helix oligomers when experimental data are not available or when they cannot help to interpret helix-helix association. We
3: Self-assemblies of amphiphilic cyclodextrins. Complete details PMID:17665188
Roux M Perly B Djedaïni-Pilard F
Eur Biophys J 36 8 861-7 , 2007 Nov
Cyclodextrins are natural cyclic oligosaccharides widely used as "molecular cages" in the pharmaceutical, agrochemical, food and cosmetical industries. The optimization of their pharmacological properties has led to the synthesis
4: H2A and H2B tails are essential to properly reconstitute nucleosome core particles. Complete details PMID:17882413
Bertin A Durand D Renouard M Livolant F Mangenot S
Eur Biophys J 36 8 1083-94 , 2007 Nov
The conformation of recombinant Nucleosome Core Particles (NCPs) lacking H2A and H2B histone tails (gH2AgH2B) are studied. The migration of these particles in acrylamide native gels is slowed down
5: Lipids as modulators of membrane fusion mediated by viral fusion proteins. Complete details PMID:17882414
Teissier E Pécheur EI
Eur Biophys J 36 8 887-99 , 2007 Nov
Enveloped viruses infect host cells by fusion of viral and target membranes. This fusion event is triggered by specific glycoproteins in the viral envelope. Fusion glycoproteins belong to either
6: Functional membrane diffusion of G-protein coupled receptors. Complete details PMID:17899063
Baker A Saulière A Dumas F Millot C Mazères S Lopez A Salomé L
Eur Biophys J 36 8 849-60 , 2007 Nov
G-protein-coupled receptor function involves interactions between the receptor, G-proteins and effectors in the cell plasma membrane. The main biochemical processes have been individually identified but the mechanisms governing the
7: Pulmonary delivery of nucleic acids. Complete details PMID:17970661
Birchall J
Expert Opin Drug Deliv 4 6 575-8 , 2007 Nov
The lung is an appropriate present and future target for gene therapy approaches designed to treat inherited monogenic diseases, eradicate bronchial tumours, transfer pharmacologically active products to the general
8: Vesicles as tools for the modulation of skin permeability. Complete details PMID:17970662
Dubey V Mishra D Nahar M Jain NK
Expert Opin Drug Deliv 4 6 579-93 , 2007 Nov
Human skin is a remarkably efficient barrier designed to keep our insides in and the outside out. The modulation of this efficient barrier's properties, including its permeability to chemicals,
9: The nanoscale in pulmonary delivery. Part 1: deposition, fate, toxicology and effects. Complete details PMID:17970663
Rogueda PG Traini D
Expert Opin Drug Deliv 4 6 595-606 , 2007 Nov
This two-part review explores the nanoscale in inhalation delivery. The first part covers the deposition, fate, toxicity and effects of nanoparticles delivered via inhalation. The second part analyses the
10: The nanoscale in pulmonary delivery. Part 2: formulation platforms. Complete details PMID:17970664
Rogueda PG Traini D
Expert Opin Drug Deliv 4 6 607-20 , 2007 Nov
This article is the second part of a review on the nanoscale in pulmonary drug delivery. Specifically it summarises and analyses the potential of the different inhalation delivery routes:
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