Embryonic development is the generation of a multicellular organism from a single cell. During this process, tissues and organs are differentiated and positioned at different parts of the organism. In animals, Embryonic development consists of 4 stages: Cleavage, Patterning, Differentiation and Growth. Mammalian Cleavage is strikingly different from most other patterns of Embry...[ Mouse Early Embryo Development view details ]

An Embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination. In Humans, it is called an Embryo from the moment of Fertilization until the end of the 8th week of gestational age, whereafter it is instead called a Fetus. In organisms that reproduce sexually, once a Sperm fertilizes...[ Human Early Embryo Development view details ]

Heart is the first organ to form and function in the Embryo, and all subsequent events in the life of the organism depend on the Heart's ability to match its output with the organism's demands for Oxygen and nutrients. Abnormalities in Heart formation, the most common form of Human birth defects, affect nearly 1% of newborns, and their frequency in spontaneously aborted pregnan...[ Factors Promoting Cardiogenesis in Vertebrates view details ]

Stem cells are undifferentiated cells capable of producing virtually all cell types in our body. They are characterized by the ability to Self-renew and maintain Pluripotency. For proper developmental outcome, ESCs (Embryonic Stem Cells) must tightly regulate their differentiation status. Hundreds of genes have been identified, including several transcription factors, which hav...[ Oct4 in Mammalian ESC Pluripotency view details ]

Stem Cells are undifferentiated cells that can give rise to several lineages of differentiated cell types. They are the founder cells for every organ, tissue and cell in the body. Stem cells are characterized by the ability to self-renew and maintain Pluripotency. These features allow Stem Cells to fulfill their multiple functions, namely to provide enough cells during organoge...[ Transcriptional Regulatory Network in Embryonic Stem Cell view details ]

ESCs (Embryonic stem cells) are Pluripotent cells derived from the ICM (Inner Cell Mass) of Blastocyst-stage embryos. These cells have two distinctive properties: an unlimited capacity for Self-renewal and Pluripotency. The capability for Self-renewal and the Pluripotency of ESCs seem to be under the control of multiple transcriptional factors, most common among them being ...[ Nanog in Mammalian ESC Pluripotency view details ]

ESCs (Embryonic Stem Cells) are a population of Pluripotent, Self-renewing cells which can proliferate indefinitely and contribute to the formation of basically all cell types in vitro and in vivo. The study of mammalian ESCs, especially Mouse ESCs, has provided valuable insights into early embryogenesis in mammals. Mouse ES cells are derived mainly from the ICM (Inner Cell Mas...[ Embryonic Stem Cell Pluripotency in Mouse view details ]

ESCs (Embryonic Stem Cells) are Pluripotent cells capable of differentiating into any cell type of the body. Only three species of Mammals have yielded long-term cultures of self-renewing ESCs- Mice, Monkeys, and Humans. Human ESCs are derived from Blastocysts, multicellular structures originating from four cleavages of fertilized oocytes. Isolated from the ICM (Inner Cell Mass...[ Human Embryonic Stem Cell Pluripotency view details ]

Stem Cells are undifferentiated cells with broad developmental potential. They are able to generate various specialized cell types and, in addition, have the capacity to self-renew and thus to produce undifferentiated progeny that retain Stem Cell features. These properties allow Stem Cells to provide developing organs with appropriate numbers of differentiated cells and to con...[ Embryonic Cell Differentiation into Cardiac Lineages view details ]

Cellular Lipid homeostasis in mammalian cells is regulated through the end-product feedback regulation of Lipid synthesis by a family of membrane-bound transcription factors designated SREBPs (Sterol Regulatory Element–Binding Proteins) that control the flux of cellular metabolites into the major Lipid pathways. The mammalian cell continuously adjusts its Sterol content by regu...[ SREBP Proteolysis view details ]