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About us | |
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ProteinLounge is a leader in the field of system biology. We have developed
many interactive web-based databases and software to help the life-scientists
understand the complexity of systems biology. Systems biology efforts focus on
understanding cellular networks, protein interactions involved in cell
signaling, mechanisms of cell survival and apoptosis leading to development or
identification of drug candidates against a variety of diseases. In the
post-genomic era, one of the major concerns for life-science researchers is the
organization of gene/protein data. Protein Lounge has met this concern by
organizing all necessary data about genes/proteins into one portal.
ProteinLounge has revolutionized bioinformatics by constructing the first complete
siRNA target database, a complete Peptide-Antigen target database and a
Kinase-Phosphatase database. We have also developed the largest database of
illustrated signal transduction pathways, which are interconnected to our
extensive protein database and online gene/protein analysis tools. Protein
Lounge is an ideal site for both life-science researchers as well as students.
Our information is very detailed and still explained in an easily understandable
manner. You can view a list of our current databases and tools below. | |
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Pathway | |
The Pathway Database is the largest collection of signaling transduction and
metabolic pathways. All pathways include extensive reviews and detailed protein
information. All proteins in each pathway are linked to detailed information
about them. The pathway database is a foundation for understanding the mechanism
of cellular signaling and an essential tool for any researcher. | |
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siRNA Database | |
The siRNA Database contains siRNA targets against all known mRNA sequences
throughout a variety of organisms. The database has also been subdivided into
folders for siRNA against Kinases, Phosphatases, Transcription Factors and
Disease genes. All siRNA targets are linked to Protein Lounge's online siRNA
cloning tool, which allows one to chose from a wide variety of vectors. | |
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Peptide-Antigen Database | |
The Peptide-Antigen Database contains antigenic peptide targets against all
known protein sequences throughout a variety of organisms. The database has also
been subdivided into folders for peptide regions for Kinases, Phosphatases,
Transcription Factors and Disease genes. All peptide targets are linked to
Protein Lounge's proprietary online hyrdoplotting tool, which allows you to view
an interactive version of the protein sequence on a hydrophilicity/phobicity
plot. | |
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Protein Interaction Database | |
The Protein Interaction Database has been developed to assist researchers in
understanding the protein-protein interactions which occur in our cells. This
database lists thousands of Human protein-protein interactions. The Protein
Interaction Database allows one to search for a protein, then view all of the
other proteins which it activates, inhibits or binds to. This database also
indicates the interactions which proteins have with other molecules such as DNA,
as well as downstream affects which occur from the protein interactions. These
protein interactions are required for proper signal tranduction and play an
essential role in all functions of our cells. | |
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Kinase-Phosphatase Database | |
The Kinase-Phosphatase Database is a list of all protein kinases and protein
phosphatases organized with their substrates. This database allows one to search
by kinases, phosphatases or by the substrates. The kinases and phosphatases are
arranged so that you can view common substrates among them. | |
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Transcription Factors Database | |
The Transcription Factor Database contains all necessary information about the
transcription factors such as its classification, specific functions, DNA
sequence, domains, structures, interaction with other proteins, its allied
members and role in specific diseases. | |
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Disease Genes Database | |
The Disease Genes Database is an accumulation of hundreds of diseases linked to
the genes which are responsible for causing the disease. You have the option of
searching by disease name and viewing the genes of the disease or you can search
by gene name and view all of the diseases which that gene causes. | |
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Biochemical Compound Database | |
The Biochemical Compound Database contains text and graphics describing
important molecules commonly involved in cellular signaling, biosynthesis and
metabolism. For each molecule, the database currently provides a large amount of
automated data including synonyms, reaction information, disease specifications
and related pathways. By clicking on the corresponding molecule directly from
the main list, its full description can be viewed. | |
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Protein Database | |
The Protein Database contains all necessary information for proteins. Proteins
have datasheets, reviews, signaling pathway relation, disease relation,
sequences, publications and reagent links. Typically, in order to obtain such a
variety of data about a protein you would have to search multiple databases. In
the Protein Lounge Protein Database all of this info is placed in a
well-organized folder system, which allows you to access the necessary data from
one page. | | | | | | |
Pathways Builder Tool | |
Pathway Builder Tool is a desktop application, which offers you the ultimate
freedom to make your own pathways using premade membranes, organelles, proteins
and other necessary pathway structures.You may also modify many premade pathways
to suit your needs. This is an ideal tool to help in the illustration of your
publications. | |
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Protein Hydroplotter | |
Protein Hydroplotter allows for the viewing of hydrophilic and hydrophobic
regions of a protein sequence. View plots for Kyte-Doolittle and Hoppman-Woods.
The plots are interactive, so one can highlight a region on the graph and the
corresponding region on the sequence. | |
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Peptide Finder | |
Peptide Antigen Finder tool finds the best antigenic peptides of a protein
sequence. Hydrophilic regions of the protein sequence are screened to find the
best possible peptides which can be used as antibody or drug targets. | |
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Easy siRNA | |
Easy siRNA offers an efficient method of finding siRNA targets and cloning them
online. The tool is based on the Tuschl algorithm to generate siRNA targets. | |
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Clone Easy | |
Clone Easy offers the easiest and most efficient method for PCR cloning online.
Enter any sequence and choose from a library of cloning vectors and enzymes.
Design primers from Genbank sequence or your own sequence. | |
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Protein Vision | |
Protein Vision is an online 3D protein structure visualization tool. Choose from
Protein Lounge's database of protein structures. View the backbone and the
molecular structure of proteins | |
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