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Sat, 25 Feb 2017 10:21:26 EST
Alzheimer's drug prescribed off-label could pose risk for some
Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test. Researchers discovered that for people who carry a specific genetic variation -- the K-variant of butyrylcholinesterase, or BChE-K -- donezpezil could accelerate cognitive decline.
Sat, 25 Feb 2017 10:21:16 EST
Antibiotics used to treat cystic fibrosis increases risk of permanent hearing loss
A powerful class of antibiotics provides life-saving relief for people with cystic fibrosis; however, a new study for the first time reveals the levels at which high cumulative dosages over time significantly increases the risk of permanent hearing loss in these patients. The study suggests physicians who treat patients with cystic fibrosis may be able to consider alternative strategies for treating the symptoms of respiratory infections associated with CF.
Fri, 24 Feb 2017 16:06:50 EST
Novel 'barcode' tracking of T cells in immunotherapy patients identifies likely cancer-killers
A new discovery makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer.
Fri, 24 Feb 2017 16:06:44 EST
Decoding the genome's cryptic language
Bioengineers have developed a new tool to identify RNA-DNA interactions. The tool can provide a full account of all the RNA molecules that interact with a segment of DNA, as well as the locations of all these interactions -- in just a single experiment. The research is a step toward identifying new functions and instructions encoded in the genome.
Fri, 24 Feb 2017 16:06:32 EST
New pop-up strategy inspired by cuts, not folds
Origami-inspired materials use folds in materials to embed powerful functionality. However, all that folding can be pretty labor intensive. Now, researchers are drawing material inspiration from another ancient Japanese paper craft -- kirigami.
Fri, 24 Feb 2017 16:06:29 EST
New structural studies reveal workings of a molecular pump that ejects cancer drugs
Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs.
Fri, 24 Feb 2017 16:06:26 EST
The making of music
A new study suggests that music -- and specifically infant-directed song -- evolved as a way for parents to signal to children that their needs are being met, while still freeing up parents to perform other tasks, like foraging for food, or caring for other offspring.
Fri, 24 Feb 2017 13:39:23 EST
New software allows for 'decoding digital brain data'
New software allows for 'decoding digital brain data' to reveal how neural activity gives rise to learning, memory and other cognitive functions. The software can be used in real time during an fMRI brain scan.
Fri, 24 Feb 2017 13:39:20 EST
Antibiotic resistance: A burgeoning problem for kids too
In a new, first-of-its-kind study, researchers have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.
Fri, 24 Feb 2017 13:39:18 EST
Nano-sized hydrogen storage system increases efficiency
An efficient hydrogen storage system has been developed that could be a boon for hydrogen powered vehicles.
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