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Sat, 21 May 2016 07:15:17 EDT
Pathogen: Temperature influences gene expression, life cycle in vibrio cholerae
Vibrio cholerae infects roughly four million people annually, worldwide, causing severe diarrheal disease, and killing an estimated 140,000 people. Its success as a pathogen belies the challenges this bacterium faces. The waters this bacterium inhabits when it's not infecting H. sapiens can be 40 degrees Fahrenheit cooler than our normal body temperature. Now a team of investigators provides new insights into how different temperatures in the bacterium's environment control expression of genes required for life at those temperatures.
Sat, 21 May 2016 07:14:12 EDT
Neutrons probe structure of enzyme critical to development of next-generation HIV drugs
Medical researchers used neutron analysis to better understand a protein implicated in the replication of HIV, the retrovirus that causes AIDS. The enzyme, known as HIV-1 protease, is a key drug target for HIV and AIDS therapies. The multi-institutional team used neutron crystallography to uncover detailed interactions of hydrogen bonds at the enzyme’s active site, revealing a pH-induced proton ‘hopping’ mechanism that guides its activity.
Sat, 21 May 2016 07:14:10 EDT
Low-salt diets may not be beneficial for all, study suggests
A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption. The study suggests that the only people who need to worry about reducing sodium in their diet are those with hypertension (high blood pressure) and have high salt consumption.
Sat, 21 May 2016 07:12:15 EDT
Bacteria in branches naturally fertilize trees
Scientists have demonstrated that poplar trees growing in rocky, inhospitable terrain harbor bacteria within them that could provide valuable nutrients to help the plant grow.
Sat, 21 May 2016 07:12:13 EDT
Lingcod meet rockfish: Catching one improves chances for the other
Researchers found that selectively fishing for lingcod in protected areas actually avoided hampering the recovery of other fish, including rockfish species listed as overfished.
Sat, 21 May 2016 07:12:11 EDT
Nanotubes are beacons in cancer-imaging technique
Strong LED light, a unique detector and targeted nanotubes combine to offer a new way to pinpoint the location of cancer tumors, according to scientists.
Sat, 21 May 2016 07:12:09 EDT
Breaking down cancer cell defenses
The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers. Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first-line treatment for cancers (mainly lung) driven by a receptor called EGFR.
Sat, 21 May 2016 07:12:06 EDT
Tiny packages may pack powerful treatment for brain tumors
A study using nanotechnology to treat brain tumors got such good results, the researchers initially questioned themselves. But further testing showed the results held up.
Sat, 21 May 2016 07:12:03 EDT
Chemists settle longstanding debate on how methane is made biologically
Like the poet, microbes that make methane are taking chemists on a road less traveled: Of two competing ideas for how microbes make the main component of natural gas, the winning chemical reaction involves a molecule less favored by previous research, something called a methyl radical. Reported today the work is important for understanding not only how methane is made, but also how to make things from it.
Sat, 21 May 2016 07:12:01 EDT
World report on fertility treatments reveals high use of intracytoplasmic sperm injection
Experts have attacked the rising use of intracytoplasmic sperm injection (ICSI) for the treatment of infertility, following publication of the latest world report on assisted reproductive technologies.
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